HCID 86726352, compound → HCID 86578306, compound

HRID 629787Notes

Reaction equation

HRID 629787 reaction equation
[N:1]([C@@H:4]([C@@H:8]([C:15]1[CH:20]=[CH:19][C:18]([F:21])=[CH:17][CH:16]=1)[CH:9]1[CH2:14][CH2:13][O:12][CH2:11][CH2:10]1)[C:5]([OH:7])=O)=[N+]=[N-].[NH2:22][C:23]1[CH:24]=[N:25][CH:26]=[C:27]([F:54])[C:28]=1[CH2:29][CH2:30][C@H:31]1[O:36][CH2:35][C@H:34]([CH2:37][O:38][C:39]([NH:41][CH2:42][C:43]([F:46])([F:45])[F:44])=[O:40])[N:33](C(OC(C)(C)C)=O)[CH2:32]1>>[F:21][C:18]1[CH:19]=[CH:20][C:15]([C@@H:8]([CH:9]2[CH2:14][CH2:13][O:12][CH2:11][CH2:10]2)[C@@H:4]([C:5]([NH:22][C:23]2[CH:24]=[N:25][CH:26]=[C:27]([F:54])[C:28]=2[CH2:29][CH2:30][C@H:31]2[O:36][CH2:35][C@@H:34]([CH2:37][O:38][C:39](=[O:40])[NH:41][CH2:42][C:43]([F:45])([F:46])[F:44])[NH:33][CH2:32]2)=[O:7])[NH2:1])=[CH:16][CH:17]=1

Participants

3

Reactant 2

HCID 86726352HCID 86726352, compoundHCID 86726400HCID 86726400, compound

Product 1

HCID 86578306HCID 86578306, compound

Procedure

The title compound was prepared from the product of step 1 and the product of step 4 of Example 89 using the procedures given in steps 2-4 of Example 93. MS (ES) m/z=630 (M+H)+.

Sources & evidence

ORD record
ord-1de6b16d18a440db9e8d5a3d6a50676a
Source dataset
uspto-grants-2016_04
Patent number
US09315475B2

Reaction notes

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