反应详情

3-Chloromethyl-2-cyclopropylmethylsulfanyl-pyridine (41 mg, 0.19 mmol) obtained in Step C of Preparation Example 18 and 2-(3-chloro-4-hydroxy-phenyl)-cyclopropane carboxylic acid ethyl ester (50 mg, 0.21 mmol) obtained in Step B of Preparation Example 47 were used to react sequentially in the same manner as in Steps A and B of Example 1 to obtain the title compound (72 mg, 90%).

1. customto react sequentially in the same manner as in Steps A and B of Example 1