HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 67812897, compound → [6-(2-Cyclopentylsulfanyl-pyridin-3-ylmethoxy)-7-methyl-benzofuran-3-yl]-acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 67812897 | HCID 67812897 | — |
| Reactant | 3-Chloromethyl-2-cyclopentylsulfanyl-pyridine | HCID 90118283 | — |
| Product | [6-(2-Cyclopentylsulfanyl-pyridin-3-ylmethoxy)-7-methyl-benzofuran-3-yl]-acetic acid | HCID 74221672 | 83.9% |
Reaction Steps
3-Chloromethyl-2-cyclopentylsulfanyl-pyridine (21 mg, 0.09 mmol) obtained in Step C of Preparation Example 8 and (6-hydroxy-7-methyl-benzofuran-3-yl)-acetic acid methyl ester (21 mg, 0.09 mmol) obtained in Preparation Example 54 were used to react sequentially in the same manner as in Steps A and B of Example 1 to obtain the title compound (30 mg, 83%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09447044B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-4b9a8b2ef709491abe4fe00f58bc3137 |
| Source note | uspto-grants-2016_09 |