Triacetoxyperiodinane → 1-(5-(2-Fluorophenyl)pyrimidin-2-yl)-6-(morpholine-4-carbonyl)-1H-indole-3-carbaldehyde

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Reaction Steps

Dess Martin periodinane (235 mg, 0.556 mmol, 1.5 eq) was added to the product of 27d) (160 mg, 0.370 mmol, 1.0 eq) in dichloromethane (10 mL) at 0° C. The mixture was stirred for 2 h at room temperature, and then filtered through a pad of celite. The filter was rinsed with dichloromethane and the filtrate was dried over sodium sulfate, and evaporated. White solid. Yield: 140 mg. Mass spectroscopy: m/z: [M+H]+=430.9

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