(1H-Indol-6-yl)(morpholino)methanone → (3-(Ethylthio)-1H-indol-6-yl)(morpholino)methanone

HRID 630458Notes

Reaction equation

HRID 630458 reaction equation
[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[C:7]([C:10]([N:12]3[CH2:17][CH2:16][O:15][CH2:14][CH2:13]3)=[O:11])[CH:8]=2)[CH:3]=[CH:2]1.C[S:19][C:20]1C2C(=CC(C(N3CCOCC3)=O)=CC=2)N[CH:21]=1>>[CH2:20]([S:19][C:3]1[C:4]2[C:9](=[CH:8][C:7]([C:10]([N:12]3[CH2:17][CH2:16][O:15][CH2:14][CH2:13]3)=[O:11])=[CH:6][CH:5]=2)[NH:1][CH:2]=1)[CH3:21]

Participants

3

Reactant 2

HCID 39710543(1H-Indol-6-yl)(morpholino)methanoneHCID 118666043(3-(Methylthio)-1H-indol-6-yl)(morpholino)methanone

Product 1

HCID 118666292(3-(Ethylthio)-1H-indol-6-yl)(morpholino)methanone

Procedure

Synthesized from (1H-indol-6-yl)(morpholino)methanone (1.5 g, 6.52 mmol, 1.0 eq) in an analogous manner as described for 1b). Yield: 1.3 g. Mass spectroscopy: m/z: [M+H]+=291.4.

Sources & evidence

ORD record
ord-fe295b6c7e0b4f18b1cd1afc820150e1
Source dataset
uspto-grants-2016_04
Patent number
US09315490B2

Reaction notes

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