HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Bromo-2-chloropyrimidine → (1-(5-Bromopyrimidin-2-yl)-3-(ethylthio)-1H-indol-6-yl)(morpholino)methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Bromo-2-chloropyrimidine | HCID 606665 | — |
| Reactant | (3-(Ethylthio)-1H-indol-6-yl)(morpholino)methanone | HCID 118666292 | — |
| Product | (1-(5-Bromopyrimidin-2-yl)-3-(ethylthio)-1H-indol-6-yl)(morpholino)methanone | HCID 118666274 | — |
Reaction Steps
The product 29a) (1.5 g, 5.17 mmol, 1.0 eq) and 5-bromo-2-chloropyrimidine (1.0 g, 5.17 mmol, 1.0 eq) were reacted as described in procedure 1c). Yield: 700 mg. Mass spectroscopy: m/z: [M+H]+=446.6/448.7
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09315490B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-96d255c8a3064a1498b829921a79dcbb |
| Source note | uspto-grants-2016_04 |