HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 630592Generated: October 30, 2026
3-Methyl-2-butanone → HCID 86707260, compound
https://huagongshe.com/reaction/630592
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 3-Methyl-2-butanone | HCID 11251 | — |
| Reactant | HCID 86712482 | HCID 86712482 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 86707260 | HCID 86707260 | — |
Reaction Steps
A solution of 4-hydrazinyl-1-benzothiophene-7-carboxylic acid CC (208 mg, 1.0 mmole) and methyl isopropyl ketone (457 mg, 5.3 mmole) in 5 mL HOAc was heated at 120° C. for 1.5 hr and cooled down to 25° C. HOAc was removed in vacuo the product was purified with CombiFlash silica gel column chromatography (eluted with CH2Cl2/MeOH stepping gradient 100:0 to 80:20). The yield of the desired product CD was 210 mg (81%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US09315864B2 |
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| Source dataset | uspto-grants-2016_04 |
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| ORD ID | ord-278ca484ee684d2abcfb8375ea5f252c |
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| Source note | uspto-grants-2016_04 |
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