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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 630607Generated: October 29, 2026

Oxane-4-sulfonyl chloride → (2R,4S)-2-Hydroxy-4-((S)-3-methoxy-2-((S)-3-methoxy-2-(2-methylthiazole-5-carboxamido)propanamido)propanamido)-2-methyl-3-oxo-5-phenylpentyl tetrahydro-2H-pyran-4-sulfonate

https://huagongshe.com/reaction/630607

Reaction equation

Participants

RoleNameHCIDCharge
ReactantOxane-4-sulfonyl chlorideHCID 22637030—
ReactantN-((S)-1-(((S)-1-(((2S,4R)-4,5-dihydroxy-4-methyl-3-oxo-1-phenylpentan-2-yl)amino)-3-methoxy-1-oxopropan-2-yl)amino)-3-methoxy-1-oxopropan-2-yl)-2-methylthiazole-5-carboxamideHCID 86715357—
Product(2R,4S)-2-Hydroxy-4-((S)-3-methoxy-2-((S)-3-methoxy-2-(2-methylthiazole-5-carboxamido)propanamido)propanamido)-2-methyl-3-oxo-5-phenylpentyl tetrahydro-2H-pyran-4-sulfonateHCID 72737661—

Reaction Steps

Prepared according to procedures described above, by reacting tetrahydro-2H-pyran-4-sulfonyl chloride with N—((S)-1-(((S)-1-(((2S,4R)-4,5-dihydroxy-4-methyl-3-oxo-1-phenylpentan-2-yl)amino)-3-methoxy-1-oxopropan-2-yl)amino)-3-methoxy-1-oxopropan-2-yl)-2-methylthiazole-5-carboxamide. MS for C30H42N4O11S2 m/z: 699 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09315542B2
Source datasetuspto-grants-2016_04
ORD IDord-6de5b3df321242aca19421ca26c93ce2
Source noteuspto-grants-2016_04