HRID630611

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID31297

Methanesulfonyl chloride

CH3ClO2S

结构：CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)NC(=O)CN1CCOCC1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)[C@](C)(O)CO

HCID86715358

未命名化合物

PRODUCTS

生成物

结构：CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)NC(=O)CN1CCOCC1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)[C@](C)(O)COS(C)(=O)=O

HCID72737693

未命名化合物

PROCEDURE

实验过程

Prepared according to procedures described above, by reacting methanesulfonyl chloride with (S)—N—((S)-1-(((2R,4S)-1,2-dihydroxy-2,6-dimethyl-3-oxoheptan-4-yl)amino)-1-oxo-3-phenylpropan-2-yl)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide. MS for C41H61N5O10S m/z: 816 (M+H)+.

WORKUP

后处理

customPrepared

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-651179c516c2481f821a6fbd764a8ddd
来源数据集: uspto-grants-2016_04
DOI: 10.6084/m9.figshare.5104873.v1
专利: US09315542B2
来源说明: uspto-grants-2016_04

反应 SMILES

[CH3:1][S:2](Cl)(=[O:4])=[O:3].[OH:6][CH2:7][C@:8]([OH:58])([CH3:57])[C:9](=[O:56])[C@@H:10]([NH:15][C:16](=[O:55])[C@@H:17]([NH:25][C:26](=[O:54])[C@@H:27]([NH:32][C:33](=[O:53])[C@@H:34]([NH:43][C:44](=[O:52])[CH2:45][N:46]1[CH2:51][CH2:50][O:49][CH2:48][CH2:47]1)[CH2:35][CH2:36][C:37]1[CH:42]=[CH:41][CH:40]=[CH:39][CH:38]=1)[CH2:28][CH:29]([CH3:31])[CH3:30])[CH2:18][C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1)[CH2:11][CH:12]([CH3:14])[CH3:13]>>[CH3:1][S:2]([O:6][CH2:7][C@:8]([OH:58])([CH3:57])[C:9](=[O:56])[C@H:10]([CH2:11][CH:12]([CH3:13])[CH3:14])[NH:15][C:16](=[O:55])[C@H:17]([CH2:18][C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1)[NH:25][C:26](=[O:54])[C@H:27]([CH2:28][CH:29]([CH3:31])[CH3:30])[NH:32][C:33](=[O:53])[C@H:34]([CH2:35][CH2:36][C:37]1[CH:38]=[CH:39][CH:40]=[CH:41][CH:42]=1)[NH:43][C:44](=[O:52])[CH2:45][N:46]1[CH2:51][CH2:50][O:49][CH2:48][CH2:47]1)(=[O:4])=[O:3]