HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenyl chloroformate → phenyl 1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-ylcarbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenyl chloroformate | HCID 15891 | — |
| Reactant | 1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-amine | HCID 19623303 | — |
| Product | phenyl 1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-ylcarbamate | HCID 66876388 | 26% |
Reaction Steps
Using the procedure described in Example 161C, 1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-amine (1.70 g, 10.3 mmol) and phenyl chloroformate (1.88 g, 12 mmol) were reacted to afford phenyl 1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-ylcarbamate as solid (0.760 g, 26%). LC-MS (ESI) m/z 286 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09320739B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-48892d58075e4b00bc30bf0e318bf7b4 |
| Source note | uspto-grants-2016_04 |