Ethylenediamine → HCID 89825611, compound

Participants

Role	Name	HCID	Charge
Reactant	Ethylenediamine	HCID 3301	—
Reactant	Triethylamine	HCID 8471	—
Reactant	3-Bromo-N,N,1-trimethyl-1H-1,2,4-triazol-5-amine	HCID 51000292	—
Catalyst	Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)	HCID 24350	—
Solvent	Ethyl Acetate	HCID 8857	—
Product	HCID 89825611	HCID 89825611	—

Reaction Conditions

Temperature	80 °C

Reaction Steps

5-Bromo-N,N,2-trimethyl-1,2,4-triazol-3-amine (103 mg, 0.5 mmol) and copper (I) iodide (4.8 mg, 0.025 mmol) were placed in a sealed microwave vial and flushed with argon. Then ethane-1,2-diamine (1.5 ml, 22 mmol) and triethylamine (140 μL, 1 mmol) were added via siringe. The reaction mixture was heated in a microwave oven at 80° C. for 1 h. The reaction mixture was diluted with ethyl acetate, filtered through kieselguhr and the filtrate was concentrated under reduced pressure to give 97 mg (quantitative) MS(ESI) m/z=185.1 [M+1]+.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US09321724B2
Source dataset	uspto-grants-2016_04
ORD ID	ord-0d5281d1d2794ffb8a5a8ff2fc174e77
Source note	uspto-grants-2016_04