HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 68296440, compound → 2-(1-Benzyl-1H-tetrazol-5-yl)-3-methylphenylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 68296440 | HCID 68296440 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 2-(1-Benzyl-1H-tetrazol-5-yl)-3-methylphenylamine | HCID 61354074 | 100.2% |
Reaction Steps
1-Benzyl-5-(2-methyl-6-nitrophenyl)-1H-tetrazole (Intermediate 17, 0.1 g) was dissolved in ethyl acetate (20 mL) under a nitrogen atmosphere. Palladium on carbon (10%, 0.1 g) was added and the nitrogen atmosphere was replaced by hydrogen. The mixture was stirred for 4 hours and then filtered through celite. The solvent was removed by evaporation under vacuum to give the title compound as a white solid (0.09 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09321740B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-6d3fe90a13e44ea8a22bc250d14623b6 |
| Source note | uspto-grants-2016_04 |