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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 631884Generated: October 30, 2026

HCID 68296440, compound → 2-(1-Benzyl-1H-tetrazol-5-yl)-3-methylphenylamine

https://huagongshe.com/reaction/631884

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 68296440HCID 68296440—
ReactantHCID 178418361HCID 178418361—
CatalystPalladiumHCID 23938—
SolventEthyl AcetateHCID 8857—
Product2-(1-Benzyl-1H-tetrazol-5-yl)-3-methylphenylamineHCID 61354074100.2%

Reaction Steps

1-Benzyl-5-(2-methyl-6-nitrophenyl)-1H-tetrazole (Intermediate 17, 0.1 g) was dissolved in ethyl acetate (20 mL) under a nitrogen atmosphere. Palladium on carbon (10%, 0.1 g) was added and the nitrogen atmosphere was replaced by hydrogen. The mixture was stirred for 4 hours and then filtered through celite. The solvent was removed by evaporation under vacuum to give the title compound as a white solid (0.09 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09321740B2
Source datasetuspto-grants-2016_04
ORD IDord-6d3fe90a13e44ea8a22bc250d14623b6
Source noteuspto-grants-2016_04