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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 631964Generated: October 29, 2026

6-(3-Chlorophenyl)picolinic acid → 6-(3-Chloro-phenyl)-pyridine-2-carboxylic acid (1-methyl-1-oxazol-2-yl-ethyl)-amide

https://huagongshe.com/reaction/631964

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-(3-Chlorophenyl)picolinic acidHCID 24730135—
Reactantalpha,alpha-Dimethyl-2-oxazolemethanamineHCID 82418817—
Product6-(3-Chloro-phenyl)-pyridine-2-carboxylic acid (1-methyl-1-oxazol-2-yl-ethyl)-amideHCID 71105537—

Reaction Steps

The title compound was synthesized in analogy to Example 1, using 6-(3-chlorophenyl)-2-pyridinecarboxylic acid (CAN 863704-38-5) and α,α-dimethyl-2-oxazolemethanamine (CAN 1211519-76-4) as starting materials, MS (LC/MS): 341.9 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09321727B2
Source datasetuspto-grants-2016_04
ORD IDord-d9fcb0abf9f143eeac00ba5fcb0454a2
Source noteuspto-grants-2016_04