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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 631974Generated: October 26, 2026

6-(3-Chlorophenyl)picolinic acid → 6-(3-Chloro-phenyl)-pyridine-2-carboxylic acid (1-methyl-1-thiazol-2-yl-ethyl)-amide

https://huagongshe.com/reaction/631974

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-(3-Chlorophenyl)picolinic acidHCID 24730135—
Reactant2-(1,3-Thiazol-2-yl)propan-2-amineHCID 28286203—
Product6-(3-Chloro-phenyl)-pyridine-2-carboxylic acid (1-methyl-1-thiazol-2-yl-ethyl)-amideHCID 71105538—

Reaction Steps

The title compound was synthesized in analogy to Example 1, using 6-(3-chlorophenyl)-2-pyridinecarboxylic acid (CAN 863704-38-5) and α,α-dimethyl-2-thiazolemethanamine (CAN 1082393-38-1) as starting materials, MS (LC/MS): 358.0 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09321727B2
Source datasetuspto-grants-2016_04
ORD IDord-5fc5a9a69ae9433597a7c6bd8475bc81
Source noteuspto-grants-2016_04