HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 2-Amino-2-ethyl-N,N-dimethylbutanamide hydrogen chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | tert-Butyl 3-(dimethylcarbamoyl)pentan-3-ylcarbamate | HCID 86674741 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 2-Amino-2-ethyl-N,N-dimethylbutanamide hydrogen chloride | HCID 86674742 | — |
Reaction Steps
tert-Butyl 3-(dimethylcarbamoyl)pentan-3-ylcarbamate (0.12 g, 0.47 mmol) was added to a saturated solution of hydrochloride in ethyl acetate (5 mL) and the mixture was stirred overnight. The solvent was removed by reduced pressure to give the crude product (0.1 g); MS (EI): m/e=159.2 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09321727B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-dcdf1c88eeb046d68c10de9fc96ac039 |
| Source note | uspto-grants-2016_04 |