HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 5-Methyl-6-sulfo-pyridine-2-carboxylic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Methanol | HCID 887 | — |
| Reactant | 5-Methyl-6-sulfo-pyridine-2-carboxylic acid | HCID 86674744 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 5-Methyl-6-sulfo-pyridine-2-carboxylic acid methyl ester | HCID 86674745 | — |
Reaction Steps
To a mixture of 5-methyl-6-sulfo-pyridine-2-carboxylic acid (0.8 g, 3.69 mmol) in methanol (20 mL) was added 4 N hydrogen chloride in dioxane (8 mL). The mixture was stirred overnight at room temperature. Undissolved solid was filtered off, and the filtrate was concentrated to give the product as yellow solid 0.5 g; MS (EI): m/e=232.0 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09321727B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-abb0d60a5d7047a485f8d8066952afef |
| Source note | uspto-grants-2016_04 |