2-Methyl-4-morpholinobutan-2-amine → HCID 71105558, compound

HRID 632021Notes

Reaction equation

HRID 632021 reaction equation
[CH:1]1([CH2:4][O:5][C:6]2[N:11]=[C:10]([C:12]([OH:14])=O)[CH:9]=[CH:8][C:7]=2[N:15]2[CH2:19][CH2:18][CH2:17][CH2:16]2)[CH2:3][CH2:2]1.[CH3:20][C:21]([NH2:31])([CH3:30])[CH2:22][CH2:23][N:24]1[CH2:29][CH2:28][O:27][CH2:26][CH2:25]1>>[CH3:30][C:21]([NH:31][C:12]([C:10]1[CH:9]=[CH:8][C:7]([N:15]2[CH2:19][CH2:18][CH2:17][CH2:16]2)=[C:6]([O:5][CH2:4][CH:1]2[CH2:2][CH2:3]2)[N:11]=1)=[O:14])([CH3:20])[CH2:22][CH2:23][N:24]1[CH2:25][CH2:26][O:27][CH2:28][CH2:29]1

Participants

3

Reactant 2

HCID 595112562-Methyl-4-morpholinobutan-2-amineHCID 710877336-Cyclopropylmethoxy-5-pyrrolidin-1-yl-pyridine-2-carboxylic acid

Product 1

HCID 71105558HCID 71105558, compound

Procedure

The title compound was synthesized in analogy to Example 1, using 6-cyclopropylmethoxy-5-pyrrolidin-1-yl-pyridine-2-carboxylic acid (Example 14 a) and 1,1-dimethyl-3-morpholin-4-yl-propylamine as starting materials, MS (EI): 417.2 [M+H]+.

Sources & evidence

ORD record
ord-5b540615315f47bfa4c220f9c5bfb8f1
Source dataset
uspto-grants-2016_04
Patent number
US09321727B2

Reaction notes

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