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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 632061Generated: October 25, 2026

2-(1,3-Thiazol-2-yl)propan-2-amine → 5-Chloro-6-(3-chloro-phenyl)-pyridine-2-carboxylic acid (1-methyl-1-thiazol-2-yl-ethyl)-amide

https://huagongshe.com/reaction/632061

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(1,3-Thiazol-2-yl)propan-2-amineHCID 28286203—
Reactant5-Chloro-6-(3-chloro-phenyl)-pyridine-2-carboxylic acidHCID 71087619—
Product5-Chloro-6-(3-chloro-phenyl)-pyridine-2-carboxylic acid (1-methyl-1-thiazol-2-yl-ethyl)-amideHCID 71105569—

Reaction Steps

The title compound was synthesized in analogy to Example 1, using 5-chloro-6-(3-chloro-phenyl)-pyridine-2-carboxylic acid and α,α-dimethyl-2-thiazolemethanamine (CAN 1082393-38-1) as starting materials, MS (LC/MS): 392.0 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09321727B2
Source datasetuspto-grants-2016_04
ORD IDord-b436e342bbe647bda9f351b3d03fd3ab
Source noteuspto-grants-2016_04