HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-(3-Chlorophenyl)picolinic acid → 6-(3-Chloro-phenyl)-pyridine-2-carboxylic acid ((S)-2-cyclopropyl-1-thiazol-2-yl-ethyl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-(3-Chlorophenyl)picolinic acid | HCID 24730135 | — |
| Reactant | 6-Cyclopropylmethoxy-5-(tetrahydro-pyran-4-yl)-pyridine-2-carboxylic acid ((S)-2-cyclopropyl-1-thiazol-2-yl-ethyl)-amide | HCID 71105570 | — |
| Product | 6-(3-Chloro-phenyl)-pyridine-2-carboxylic acid ((S)-2-cyclopropyl-1-thiazol-2-yl-ethyl)-amide | HCID 71105571 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 1, using 6-(3-chlorophenyl)-2-pyridinecarboxylic acid (CAN 863704-38-5) and (S)-2-cyclopropyl-1-thiazol-2-yl-ethylamine (Example 59 b) as starting materials, MS (LC/MS): 384.1 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09321727B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-a461698bcf4a41a881a6ef257aa62e0c |
| Source note | uspto-grants-2016_04 |