6-(3-Chlorophenyl)picolinic acid → HCID 71105582, compound

HRID 632084Notes

Reaction equation

HRID 632084 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([C:8]2[N:13]=[C:12]([C:14]([OH:16])=O)[CH:11]=[CH:10][CH:9]=2)[CH:5]=[CH:6][CH:7]=1.[CH3:17][C:18]([NH2:25])([C:20]1[N:24]=[CH:23][O:22][N:21]=1)[CH3:19]>>[CH3:17][C:18]([NH:25][C:14]([C:12]1[CH:11]=[CH:10][CH:9]=[C:8]([C:4]2[CH:5]=[CH:6][CH:7]=[C:2]([Cl:1])[CH:3]=2)[N:13]=1)=[O:16])([C:20]1[N:24]=[CH:23][O:22][N:21]=1)[CH3:19]

Participants

3

Reactant 2

HCID 247301356-(3-Chlorophenyl)picolinic acidHCID 435591182-(1,2,4-Oxadiazol-3-yl)propan-2-amine

Product 1

HCID 71105582HCID 71105582, compound

Procedure

The title compound was synthesized in analogy to Example 1, using 6-(3-chlorophenyl)-2-pyridinecarboxylic acid (CAN 863704-38-5) and 1-methyl-1-[1,2,4]oxadiazol-3-yl-ethylamine (CAN 1153757-41-5) as starting materials, MS (EI): m/e=343.1 [M+H]+.

Sources & evidence

ORD record
ord-d0cedcdf3144441681b3aea2588b3292
Source dataset
uspto-grants-2016_04
Patent number
US09321727B2

Reaction notes

Loading…