2-(1,3-Thiazol-2-yl)propan-2-amine → HCID 71105585, compound

HRID 632099Notes

Reaction equation

HRID 632099 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([C:8]2[N:13]=[C:12]([C:14]([OH:16])=O)[CH:11]=[CH:10][C:9]=2[O:17][CH3:18])[CH:5]=[CH:6][CH:7]=1.[CH3:19][C:20]([CH3:27])([C:22]1[S:23][CH:24]=[CH:25][N:26]=1)[NH2:21]>>[CH3:19][C:20]([NH:21][C:14]([C:12]1[CH:11]=[CH:10][C:9]([O:17][CH3:18])=[C:8]([C:4]2[CH:5]=[CH:6][CH:7]=[C:2]([Cl:1])[CH:3]=2)[N:13]=1)=[O:16])([C:22]1[S:23][CH:24]=[CH:25][N:26]=1)[CH3:27]

Participants

3

Reactant 2

HCID 282862032-(1,3-Thiazol-2-yl)propan-2-amineHCID 710872506-(3-Chlorophenyl)-5-methoxy-pyridine-2-carboxylic acid

Product 1

HCID 71105585HCID 71105585, compound

Procedure

The title compound was synthesized in analogy to Example 1, using 6-(3-chloro-phenyl)-5-methoxy-pyridine-2-carboxylic acid and (Example 81 c) and α,α-dimethyl-2-thiazolemethanamine (CAN 1082393-38-1) as starting materials, MS (EI): m/e=388.0 [M+H]+.

Sources & evidence

ORD record
ord-a6755def6e7440d299c34bb4cb40d2eb
Source dataset
uspto-grants-2016_04
Patent number
US09321727B2

Reaction notes

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