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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 632106Generated: October 25, 2026

2-(1,2,4-Oxadiazol-3-yl)propan-2-amine → 5-Chloro-6-(3-chloro-phenyl)-pyridine-2-carboxylic acid (1-methyl-1-[1,2,4]oxadiazol-3-yl-ethyl)-amide

https://huagongshe.com/reaction/632106

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(1,2,4-Oxadiazol-3-yl)propan-2-amineHCID 43559118—
Reactant5-Chloro-6-(3-chloro-phenyl)-pyridine-2-carboxylic acidHCID 71087619—
Product5-Chloro-6-(3-chloro-phenyl)-pyridine-2-carboxylic acid (1-methyl-1-[1,2,4]oxadiazol-3-yl-ethyl)-amideHCID 71105586—

Reaction Steps

The title compound was synthesized in analogy to Example 1, using 5-chloro-6-(3-chloro-phenyl)-pyridine-2-carboxylic acid (Example 58 c) and 1-methyl-1-[1,2,4]oxadiazol-3-yl ethylamine (CAN 1153757-41-5) as starting materials, MS (EI): m/e=377.0 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09321727B2
Source datasetuspto-grants-2016_04
ORD IDord-1bf51d043c384e41a0ddb9e25e98958c
Source noteuspto-grants-2016_04