HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Chloro-6-(3-chloro-phenyl)-pyridine-2-carboxylic acid → 5-Chloro-6-(3-chloro-phenyl)-pyridine-2-carboxylic acid (1-ethyl-1-methylcarbamoyl-propyl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Chloro-6-(3-chloro-phenyl)-pyridine-2-carboxylic acid | HCID 71087619 | — |
| Reactant | 2-Amino-2-ethyl-N-methyl-butyramide | HCID 79810370 | — |
| Product | 5-Chloro-6-(3-chloro-phenyl)-pyridine-2-carboxylic acid (1-ethyl-1-methylcarbamoyl-propyl)-amide | HCID 71113197 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 1, using 5-chloro-6-(3-chloro-phenyl)-pyridine-2-carboxylic acid (Example 58 c) and 2-amino-2-ethyl-N-methyl-butyramide (Example 70 b) as starting materials, MS (EI): m/e=394.1 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09321727B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-3cc2e588b3b54c99a08cea0c2f3e97ba |
| Source note | uspto-grants-2016_04 |