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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 632129Generated: October 25, 2026

Leucinamide → 5-Chloro-6-(3-chloro-phenyl)-pyridine-2-carboxylic acid ((S)-1-carbamoyl-3-methyl-butyl)-amide

https://huagongshe.com/reaction/632129

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLeucinamideHCID 69640—
Reactant5-Chloro-6-(3-chloro-phenyl)-pyridine-2-carboxylic acidHCID 71087619—
Product5-Chloro-6-(3-chloro-phenyl)-pyridine-2-carboxylic acid ((S)-1-carbamoyl-3-methyl-butyl)-amideHCID 71105595—

Reaction Steps

The title compound was synthesized in analogy to Example 1, using 5-chloro-6-(3-chloro-phenyl)-pyridine-2-carboxylic acid (Example 58 c) and (2S)-2-amino-4-methyl-pentanamide (CAN 687-51-4) as starting materials, MS (EI): m/e=380.0 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09321727B2
Source datasetuspto-grants-2016_04
ORD IDord-250df4877f184760b35d6bce5e9fe052
Source noteuspto-grants-2016_04