1-(2-Amino-2-methylpropoxy)-2-methoxyethane → 5-Cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid [2-(2-methoxy-ethoxy)-1,1-dimethyl-ethyl]-amide

HRID 632149Notes

Reaction equation

HRID 632149 reaction equation
[CH:1]1([C:4]2[CH:5]=[CH:6][C:7]([C:15]([OH:17])=O)=[N:8][C:9]=2[O:10][CH2:11][CH:12]2[CH2:14][CH2:13]2)[CH2:3][CH2:2]1.[CH3:18][O:19][CH2:20][CH2:21][O:22][CH2:23][C:24]([NH2:27])([CH3:26])[CH3:25]>>[CH3:18][O:19][CH2:20][CH2:21][O:22][CH2:23][C:24]([NH:27][C:15]([C:7]1[CH:6]=[CH:5][C:4]([CH:1]2[CH2:2][CH2:3]2)=[C:9]([O:10][CH2:11][CH:12]2[CH2:13][CH2:14]2)[N:8]=1)=[O:17])([CH3:26])[CH3:25]

Participants

3

Reactant 2

HCID 645371681-(2-Amino-2-methylpropoxy)-2-methoxyethaneHCID 710873465-Cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid

Product 1

HCID 711056035-Cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid [2-(2-methoxy-ethoxy)-1,1-dimethyl-ethyl]-amide

Procedure

The title compound was synthesized in analogy to Example 1, using 5-cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid (Example 42 a) and 2-(2-methoxy-ethoxy)-1,1-dimethyl-ethylamine (CAN 947723-29-7) as starting materials, MS (EI): m/e=363.2 [M+H]+.

Sources & evidence

ORD record
ord-15b89ed5d4fa4dff9af89a09576cf574
Source dataset
uspto-grants-2016_04
Patent number
US09321727B2

Reaction notes

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