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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 632151Generated: October 25, 2026

2-(1,2,4-Oxadiazol-3-yl)propan-2-amine → 6-Cyclopropylmethoxy-5-trifluoromethyl-pyridine-2-carboxylic acid (1-methyl-1-[1,2,4]oxadiazol-3-yl-ethyl)-amide

https://huagongshe.com/reaction/632151

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(1,2,4-Oxadiazol-3-yl)propan-2-amineHCID 43559118—
Reactant6-Cyclopropylmethoxy-5-trifluoromethyl-pyridine-2-carboxylic acidHCID 71087457—
Product6-Cyclopropylmethoxy-5-trifluoromethyl-pyridine-2-carboxylic acid (1-methyl-1-[1,2,4]oxadiazol-3-yl-ethyl)-amideHCID 71105607—

Reaction Steps

The title compound was synthesized in analogy to Example 1, using 6-cyclopropylmethoxy-5-trifluoromethyl-pyridine-2-carboxylic acid (Example 113 d) and 1-methyl-1-[1,2,4]oxadiazol-3-yl ethylamine (CAN 1153757-41-5) as starting materials, MS (EI): m/e=371.2 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09321727B2
Source datasetuspto-grants-2016_04
ORD IDord-23b5752e5f7648c0844e8f17a5d17228
Source noteuspto-grants-2016_04