HuagongsheHuagongshe Chemistry Print Report · For research reference only
Leucinamide → 5-Cyclopropylamino-6-cyclopropylmethoxy-pyridine-2-carboxylic acid ((S)-1-carbamoyl-3-methyl-butyl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Leucinamide | HCID 69640 | — |
| Reactant | 5-Cyclopropylamino-6-cyclopropylmethoxy-pyridine-2-carboxylic acid | HCID 71087191 | — |
| Product | 5-Cyclopropylamino-6-cyclopropylmethoxy-pyridine-2-carboxylic acid ((S)-1-carbamoyl-3-methyl-butyl)-amide | HCID 71105614 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 1, using 5-cyclopropylamino-6-cyclopropylmethoxy-pyridine-2-carboxylic acid (Example 133 b) and (2S)-2-amino-4-methyl-pentanamide (CAN 687-51-4) as starting materials, MS (EI): m/e=361.3 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09321727B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-b4be1ab2b6754529bf394b7a6369b9d5 |
| Source note | uspto-grants-2016_04 |