HuagongsheHuagongshe Chemistry Print Report · For research reference only
L-(+)-Cysteine → 2-(4-(4-(3,4,5-Trimethoxybenzoyl)thiazol-2-yl)phenyl)acetonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | L-(+)-Cysteine | HCID 5862 | — |
| Reactant | 1,4-Dicyanobenzene | HCID 12172 | — |
| Reactant | 4-(3,4,5-Trimethoxybenzoyl)-2-phenylthiazole | HCID 25227430 | — |
| Product | 2-(4-(4-(3,4,5-Trimethoxybenzoyl)thiazol-2-yl)phenyl)acetonitrile | HCID 57516833 | — |
Reaction Steps
2-(4-(4-(3,4,5-Trimethoxybenzoyl)thiazol-2-yl)phenyl)acetonitrile (2n) was prepared using the same method as used of compound 1h from terephthalonitrile and cysteine. 1H NMR (500 MHz, CDCl3) δ 8.30 (s, 1H), 8.04 (d, 2H), 7.76 (s, 2H), 7.46 (d, 2H), 3.97 (s, 3H), 3.95 (s, 6H), 3.83 (s, 2H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09447049B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-280c5425dd604750a84a489ae66a65b4 |
| Source note | uspto-grants-2016_09 |