HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-2-methyl-1-propanol → N-(1-hydroxy-2-methylpropan-2-yl)-7,7-dimethyl-5,6,7,8-tetrahydroquinoline-2-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-2-methyl-1-propanol | HCID 11807 | — |
| Reactant | 7,7-Dimethyl-5,6,7,8-tetrahydro-quinoline-2-carboxylic acid | HCID 71087472 | — |
| Product | N-(1-hydroxy-2-methylpropan-2-yl)-7,7-dimethyl-5,6,7,8-tetrahydroquinoline-2-carboxamide | HCID 71087724 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 1, using 7,7-dimethyl-5,6,7,8-tetrahydro-quinoline-2-carboxylic acid (Example 143 d) and 2-amino-2-methyl-1-propanol (CAN 124-68-5) as starting materials, LC-MS (UV peak area/EIC) 99.7%, 277.1910(M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09321727B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-99d2a612306e455faa5dbf1e361d3380 |
| Source note | uspto-grants-2016_04 |