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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 63221Generated: October 26, 2026

L-(+)-Cysteine → HCID 136047812, compound

https://huagongshe.com/reaction/63221

Reaction equation

Participants

RoleNameHCIDCharge
ReactantL-(+)-CysteineHCID 5862—
Reactant4-(3,4,5-Trimethoxybenzoyl)-2-phenylthiazoleHCID 25227430—
ReactantHCID 57516834HCID 57516834—
ProductHCID 136047812HCID 136047812—

Reaction Steps

(2-(1H-Indol-2-yl)thiazol-4-yl)(1H-indol-2-yl)methanone (8) was prepared using the similar method as used of compound 1h from 2-(1H-indol-2-yl)-4,5-dihydrothiazole-4-carboxylic acid and cysteine. 1H NMR (500 MHz, CDCl3) δ 9.39 (s, 1H), 8.54 (s, 1H), 8.46 (s, 1H), 8.06 (s, 1H), 8.03 (dd, 1H), 7.66 (d, 1H), 7.51 (d, 1H), 7.41 (d, 1H), 7.33 (t, 1H), 7.29 (d, 1H), 7.15 (t, 1H), 7.09 (d, 1H), 6.72 (s, 1H). MS (ESI) m/z 366.1 (M+Na)+, 341.9 (M−H)−.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09447049B2
Source datasetuspto-grants-2016_09
ORD IDord-905e9c9e0c914d4eaf146d4e6412c6ce
Source noteuspto-grants-2016_09