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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 632215Generated: October 25, 2026

2-Amino-2-methyl-1-propanol → 5-Cyclopropylamino-6-cyclopropylmethoxy-pyridine-2-carboxylic acid (2-hydroxy-1,1-dimethyl-ethyl)-amide

https://huagongshe.com/reaction/632215

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-2-methyl-1-propanolHCID 11807—
Reactant5-Cyclopropylamino-6-cyclopropylmethoxy-pyridine-2-carboxylic acidHCID 71087191—
Product5-Cyclopropylamino-6-cyclopropylmethoxy-pyridine-2-carboxylic acid (2-hydroxy-1,1-dimethyl-ethyl)-amideHCID 71105634—

Reaction Steps

The title compound was synthesized in analogy to Example 1, using 5-cyclopropylamino-6-cyclopropylmethoxy-pyridine-2-carboxylic acid (Example 133 b) and 2-amino-2-methyl-1-propanol (CAN 124-68-5) as starting materials, MS (EI): m/e=401.1 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09321727B2
Source datasetuspto-grants-2016_04
ORD IDord-4b2fdf2c891b467ca3badcc500cbfce5
Source noteuspto-grants-2016_04