2-(5-Methyl-1,2,4-oxadiazol-3-yl)propan-2-amine → HCID 71093634, compound

HRID 632217Notes

Reaction equation

HRID 632217 reaction equation
[CH:1]1([CH2:4][O:5][C:6]2[N:11]=[C:10]([C:12]([OH:14])=O)[CH:9]=[CH:8][C:7]=2[C:15]2([OH:19])[CH2:18][CH2:17][CH2:16]2)[CH2:3][CH2:2]1.[CH3:20][C:21]([CH3:29])([C:23]1[N:27]=[C:26]([CH3:28])[O:25][N:24]=1)[NH2:22]>>[CH3:20][C:21]([NH:22][C:12]([C:10]1[CH:9]=[CH:8][C:7]([C:15]2([OH:19])[CH2:18][CH2:17][CH2:16]2)=[C:6]([O:5][CH2:4][CH:1]2[CH2:2][CH2:3]2)[N:11]=1)=[O:14])([C:23]1[N:27]=[C:26]([CH3:28])[O:25][N:24]=1)[CH3:29]

Participants

3

Reactant 2

HCID 435592512-(5-Methyl-1,2,4-oxadiazol-3-yl)propan-2-amineHCID 710876116-Cyclopropylmethoxy-5-(1-hydroxy-cyclobutyl)-pyridine-2-carboxylic acid

Product 1

HCID 71093634HCID 71093634, compound

Procedure

The title compound was synthesized in analogy to Example 1, using 6-cyclopropylmethoxy-5-(1-hydroxy-cyclobutyl)-pyridine-2-carboxylic acid and α,α,5-trimethyl-1,2,4-oxadiazole-3-methanamine (CAN 1153831-97-0) as starting materials, MS (EI): m/e=387.2 [M+H]+.

Sources & evidence

ORD record
ord-3b7e02e8a5a84b3fb3cc918249dc455f
Source dataset
uspto-grants-2016_04
Patent number
US09321727B2

Reaction notes

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