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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 632230Generated: October 25, 2026

2-Amino-2,3-dimethylbutanamide → N-(1-Amino-2,3-dimethyl-1-oxobutan-2-yl)-5-cyclopropyl-6-(cyclopropylmethoxy)picolinamide

https://huagongshe.com/reaction/632230

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-2,3-dimethylbutanamideHCID 9793773—
Reactant5-Cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acidHCID 71087346—
ProductN-(1-Amino-2,3-dimethyl-1-oxobutan-2-yl)-5-cyclopropyl-6-(cyclopropylmethoxy)picolinamideHCID 71087257—

Reaction Steps

The title compound was synthesized in analogy to Example 1, using 5-cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid (Example 42 a) and 2-amino-2,3-dimethyl-butanamide (CAN 40963-14-2) as starting materials, LC-MS (UV peak area/ESI) 96%, 346.2136 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09321727B2
Source datasetuspto-grants-2016_04
ORD IDord-1608fe9ec7ad4bb5a11e81357e2ea573
Source noteuspto-grants-2016_04