HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2S)-2-amino-N,4,4-trimethyl-pentanamide → (S)-5-Cyclopropyl-6-(cyclopropylmethoxy)-N-(4,4-dimethyl-1-(methylamino)-1-oxopentan-2-yl)picolinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2S)-2-amino-N,4,4-trimethyl-pentanamide | HCID 57635521 | — |
| Reactant | 5-Cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid | HCID 71087346 | — |
| Product | (S)-5-Cyclopropyl-6-(cyclopropylmethoxy)-N-(4,4-dimethyl-1-(methylamino)-1-oxopentan-2-yl)picolinamide | HCID 71087953 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 1, using 5-cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid (Example 42 a) and (2S)-2-amino-N,4,4-trimethyl-pentanamide (CAN 1160161-70-5) as starting materials, MS (EI): m/e=374.1 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09321727B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-732bdef2106146c6aea84aa3c6fb5a41 |
| Source note | uspto-grants-2016_04 |