HuagongsheHuagongshe Chemistry Print Report · For research reference only
R-2-Amino-2,3-dimethyl-butan-1-OL → 5-Cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid ((R)-1-hydroxymethyl-1,2-dimethyl-propyl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | R-2-Amino-2,3-dimethyl-butan-1-OL | HCID 12113027 | — |
| Reactant | 5-Cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid | HCID 71087346 | — |
| Product | 5-Cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid ((R)-1-hydroxymethyl-1,2-dimethyl-propyl)-amide | HCID 71105647 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 1, using 5-cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid (Example 42 a) and (R)-2-amino-2,3-dimethyl-butan-1-ol [CAN 155158-75-1] as starting materials, MS (EI): m/e=333.2 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09321727B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-c9f0e6bf3ca64e928f024624bcfa4cce |
| Source note | uspto-grants-2016_04 |