Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 632257Generated: October 26, 2026

6-(3-Chlorophenyl)picolinic acid → (S)-6-(3-Chlorophenyl)-N-(4,4-dimethyl-1-(methylamino)-1-oxopentan-2-yl)picolinamide

https://huagongshe.com/reaction/632257

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-(3-Chlorophenyl)picolinic acidHCID 24730135—
Reactant(2S)-2-amino-N,4,4-trimethyl-pentanamideHCID 57635521—
Product(S)-6-(3-Chlorophenyl)-N-(4,4-dimethyl-1-(methylamino)-1-oxopentan-2-yl)picolinamideHCID 71087330—

Reaction Steps

The title compound was synthesized in analogy to Example 1, using 6-(3-chlorophenyl)-2-pyridinecarboxylic acid (CAN 863704-38-5) and (2S)-2-amino-N,4,4-trimethyl-pentanamide (CAN 1160161-70-5) as starting materials, MS (EI): m/e=374.1 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09321727B2
Source datasetuspto-grants-2016_04
ORD IDord-dd8b372069ac4e559e2c3830d92b71de
Source noteuspto-grants-2016_04