2-(5-Methyl-1,2,4-oxadiazol-3-yl)propan-2-amine → HCID 71087730, compound

HRID 632261Notes

Reaction equation

HRID 632261 reaction equation
[CH:1]1([C:4]2[CH:5]=[CH:6][C:7]([C:18]([OH:20])=O)=[N:8][C:9]=2[O:10][CH2:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][N:13]=2)[CH2:3][CH2:2]1.[CH3:21][C:22]([CH3:30])([C:24]1[N:28]=[C:27]([CH3:29])[O:26][N:25]=1)[NH2:23]>>[CH:1]1([C:4]2[CH:5]=[CH:6][C:7]([C:18]([NH:23][C:22]([C:24]3[N:28]=[C:27]([CH3:29])[O:26][N:25]=3)([CH3:30])[CH3:21])=[O:20])=[N:8][C:9]=2[O:10][CH2:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][N:13]=2)[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 435592512-(5-Methyl-1,2,4-oxadiazol-3-yl)propan-2-amineHCID 710877855-Cyclopropyl-6-(pyridin-2-ylmethoxy)-pyridine-2-carboxylic acid

Product 1

HCID 71087730HCID 71087730, compound

Procedure

The title compound was synthesized in analogy to Example 1, using 5-cyclopropyl-6-(pyridin-2-ylmethoxy)-pyridine-2-carboxylic acid (Example 189 b) and α,α,5-trimethyl-1,2,4-oxadiazole-3-methanamine (CAN 1153831-97-0) as starting materials, MS (EI): m/e=394.2 [M+H]+.

Sources & evidence

ORD record
ord-7fc488d31bea46b0abd9eafcb76034f0
Source dataset
uspto-grants-2016_04
Patent number
US09321727B2

Reaction notes

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