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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 632373생성일: 2026년 10월 25일

Methyl L-tert-leucinate hydrochloride → (S)-Methyl 2-(6-(cyclopropylmethoxy)-5-(3,3-difluoroazetidin-1-yl)picolinamido)-3,3-dimethylbutanoate

https://huagongshe.com/reaction/632373

반응식

참여 물질

역할이름HCID투입량
반응물Methyl L-tert-leucinate hydrochlorideHCID 16217630—
반응물6-(Cyclopropylmethoxy)-5-(3,3-difluoroazetidin-1-yl)picolinic acidHCID 71087292—
생성물(S)-Methyl 2-(6-(cyclopropylmethoxy)-5-(3,3-difluoroazetidin-1-yl)picolinamido)-3,3-dimethylbutanoateHCID 71087806—

반응 단계

The title compound was synthesized in analogy to Example 1, using 6-(cyclopropylmethoxy)-5-(3,3-difluoroazetidin-1-yl)picolinic acid (Example 69 b) and (S)-methyl 2-amino-3,3-dimethylbutanoate hydrochloride (CAN 63038-27-7) as starting materials. MS (EI): m/e=412.3 [M+H]+.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US09321727B2
출처 데이터셋uspto-grants-2016_04
ORD IDord-646ae009300648d989e240204a85c37a
출처 메모uspto-grants-2016_04