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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 632391생성일: 2026년 10월 25일

6-(Cyclopropylmethoxy)-5-(3,3-difluoroazetidin-1-yl)picolinic acid → 6-Cyclopropylmethoxy-5-(3,3-difluoro-azetidin-1-yl)-pyridine-2-carboxylic acid (3-methyl-1-pyridazin-3-yl-butyl)-amide

https://huagongshe.com/reaction/632391

반응식

참여 물질

역할이름HCID투입량
반응물6-(Cyclopropylmethoxy)-5-(3,3-difluoroazetidin-1-yl)picolinic acidHCID 71087292—
반응물3-Methyl-1-(pyridazin-3-yl)butan-1-amineHCID 86674794—
생성물6-Cyclopropylmethoxy-5-(3,3-difluoro-azetidin-1-yl)-pyridine-2-carboxylic acid (3-methyl-1-pyridazin-3-yl-butyl)-amideHCID 71105703—

반응 단계

In analogy to the procedure described in Example 293, 6-(cyclopropylmethoxy)-5-(3,3-difluoroazetidin-1-yl)picolinic acid (Example 69 b) and 3-methyl-1-(pyridazin-3-yl)butan-1-amine were condensed to the title product. MS (EI): m/e=432.4 [M+H]+.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US09321727B2
출처 데이터셋uspto-grants-2016_04
ORD IDord-17169a058d3645fcbf4517f738fbfe53
출처 메모uspto-grants-2016_04