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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 632402Generated: October 29, 2026

5-Cyclopropyl-6-(4-fluoro-benzyl)-pyridine-2-carboxylic acid → HCID 71105712, compound

https://huagongshe.com/reaction/632402

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Cyclopropyl-6-(4-fluoro-benzyl)-pyridine-2-carboxylic acidHCID 71087698—
Reactant(S)-2,2,2-trifluoro-1-(pyridin-2-yl)ethan-1-amine hydrochlorideHCID 71087990—
ProductHCID 71105712HCID 71105712—

Reaction Steps

The title compound was synthesized in analogy to Example 1, using 5-cyclopropyl-6-(4-fluoro-benzyl)-pyridine-2-carboxylic acid (Example 155 g) and (S)-2,2,2-trifluoro-1-(pyridin-2-yl)ethanamine hydrochloride (CAN 336105-45-4) as starting materials. MS (EI): m/e=430.3 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09321727B2
Source datasetuspto-grants-2016_04
ORD IDord-5e0961d567fd4b33825a4ebd2f0978ad
Source noteuspto-grants-2016_04