Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 632441Generated: October 29, 2026

L-Homoserine lactone → 5-Cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid ((S)-2-oxo-tetrahydro-furan-3-yl)-amide

https://huagongshe.com/reaction/632441

Reaction equation

Participants

RoleNameHCIDCharge
ReactantL-Homoserine lactoneHCID 445963—
Reactant5-Cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acidHCID 71087346—
Product5-Cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid ((S)-2-oxo-tetrahydro-furan-3-yl)-amideHCID 71105748—

Reaction Steps

The title compound was synthesized in analogy to Example 1, using 5-cyclopropyl-6-cyclopropylmethyloxy-pyridine-2-carboxylic acid (Example 42a) and (35)-3-aminodihydro-2(3H)-furanone (CAN 2185-02-6) as starting materials; LC-MS (UV peak area/ESI) 100%, 317.1500 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09321727B2
Source datasetuspto-grants-2016_04
ORD IDord-cb1de3f69d9546d3b882e1dab1c38498
Source noteuspto-grants-2016_04