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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 632468Generated: October 30, 2026

Hydrochloric Acid → HCID 90273387, compound

https://huagongshe.com/reaction/632468

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 90273376HCID 90273376—
SolventDiethyl EtherHCID 3283—
SolventDichloromethaneHCID 6344—
ProductHCID 90273387HCID 90273387—

Reaction Steps

To a solution of 4-[5-(2-amino-5-p-tolyl-pyridin-3-yl)-[1,3,4]oxadiazol-2-yl]-piperidine-1-carboxylic acid tert-butyl ester (250 mg, 0.574 mmol) in DCM (20 mL) was added 2M HCl in diethyl ether (20 mL) at 0° C. The reaction mixture was allowed to warm to ambient temperature, and was stirred for 2 h. After completion of the reaction, reaction mixture was filtered and washed with diethyl ether (2×30 mL), which afforded the title compound as a yellow solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09321748B2
Source datasetuspto-grants-2016_04
ORD IDord-0dcdcf943c984d99957f551f765979ae
Source noteuspto-grants-2016_04