5-(Benzyloxy)-2-tert-butylpyridine → 6-Tert-butylpyridin-3-ol

Beteiligte Stoffe

Reaktionsschritte

To a stirred solution of 2-(1,1-dimethylethyl)-5-[(phenylmethyl)oxy]pyridine, (5.3 g) in ethanol (150 ml) was added 20% Pd(OH)2 (12.3 g) at 25-30 C. The above mixture was purged with hydrogen for 3 h until it had gone to completion by tlc. The reaction mixture was filtered through celite and the filtrate concentrated in vacuo and purified to give the title compound, 3.9 g

Herkunft & Nachweise