HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 58072731, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | HCID 58072964 | HCID 58072964 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 58072731 | HCID 58072731 | — |
Reaction Steps
The title compound is synthesized according to general procedure GP3 starting from 2.82 g (11.0 mmol) 6-trifluoromethyl-5-trimethylsilanylethynyl-pyridin-2-ylamine and 757 mg (5.5 mmol) K2CO3 in 25 mL MeOH. The product is purified by chromatography on silica gel using a cyclohexane/ethyl acetate gradient. Yield: 0.9 g (44%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09321771B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-8439e87d0073486ba6fad6d06efecb4e |
| Source note | uspto-grants-2016_04 |