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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 6329Generated: October 25, 2026

L-tert-Leucine → (2S)-2-Amino-3,3-dimethylbutanamide

https://huagongshe.com/reaction/6329

Reaction equation

Participants

RoleNameHCIDCharge
ReactantL-tert-LeucineHCID 164608—
Reactant2-Amino-3,3-dimethylbutanamideHCID 3496444—
Reactant(2R)-2-Amino-3,3-dimethylbutanamideHCID 10197708—
Product(2S)-2-Amino-3,3-dimethylbutanamideHCID 11297986—

Reaction Steps

In the same way as in example VIII, an incubation was carried out with DL-tertiary leucine amide. Analysis of the remaining reaction mixture after 8 hours showed that both L-tertiary leucine and D-tertiary leucine amide with an e.e. of ≥99% were present in the reaction mixture.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05248608
Source datasetuspto-grants-1993_09
ORD IDord-ea88f85ac3924f1abb143061996c57cd
Source noteuspto-grants-1993_09