Sodium Hydroxide → HCID 178525561, compound

Participants

Reaction Steps

Trans-{4-[4-(3-{[2-(2,6-dichlorophenyl)-5-trifluoromethyloxazole-4-carbonyl]amino}propionylamino)phenyl]cyclohexyl}acetate methyl ester (150 mg, 0.239 mmol) was put into THF/water (20 mL, 3:1) solvent, then NaOH (14.37 mg, 1.437 mmol) was added thereto and stirred at room temperature for 24 hours. After THF was removed, a desired sodium salt solid was washed with water to obtain a final compound (150 mg, 98%).

Provenance & Evidence