HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromo-1-chloro-4-nitrobenzene → 2-(2-Chloro-5-nitrophenyl)pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromo-1-chloro-4-nitrobenzene | HCID 2735549 | — |
| Reactant | HCID 178418723 | HCID 178418723 | — |
| Product | 2-(2-Chloro-5-nitrophenyl)pyridine | HCID 40151923 | — |
Reaction Steps
Procedure B was performed with 2-pyridylzinc bromide (4 mL, 2.0 mmol, 0.5 M in THF) and 3-bromo-4-chloro-nitrobenzene (236 mg, 1.0 mmol). Purified by chromatography on silica gel (10% ethyl acetate/hexanes) to yield 2-(2-chloro-5-nitrophenyl)pyridine as a light yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09321761B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-5aa67a9b594248cfab574e8c42d8b95c |
| Source note | uspto-grants-2016_04 |