HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methylpiperazine → HCID 58614795, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methylpiperazine | HCID 53167 | — |
| Reactant | 4-(Bromomethyl)-N-[4-chloro-3-(2-pyridinyl)phenyl]benzamide | HCID 66878170 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 58614795 | HCID 58614795 | — |
Reaction Steps
4-(bromomethyl)-N-(4-chloro-3-(pyridin-2-yl)phenyl)benzamide (85 mg) was dissolved in DMSO (1 mL) and stirred for 1 h with methylpiperazine. The reaction mixture was concentrated, and the crude residue was purified by reverse phase HPLC to yield N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-((4-methylpiperazin-1-yl)methyl)benzamide. MS (Q1) 421.3 (M)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09321761B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-36c1a20ecf2241b4acdda0bbfe531d1a |
| Source note | uspto-grants-2016_04 |