Sec-Butylamine → 3-[(sec-butylamino)sulfonyl]benzoic acid

HRID 633002Notes

Reaction equation

Cl[S:2]([C:5]1[CH:6]=[C:7]([CH:11]=[CH:12][CH:13]=1)[C:8]([OH:10])=[O:9])(=[O:4])=[O:3].[CH:14]([NH2:18])([CH2:16][CH3:17])[CH3:15]>>[CH:14]([NH:18][S:2]([C:5]1[CH:6]=[C:7]([CH:11]=[CH:12][CH:13]=1)[C:8]([OH:10])=[O:9])(=[O:4])=[O:3])([CH2:16][CH3:17])[CH3:15]

Participants

Reactant 2

HCID 24874Sec-Butylamine

HCID 77641Benzoic acid, 3-(chlorosulfonyl)-

Product 1

HCID 48683723-[(sec-butylamino)sulfonyl]benzoic acid

Procedure

Procedure H was performed to couple 3-(chlorosulfonyl)benzoic acid with sec-butyl amine to produce 3-(sec-butylsulfamoyl)benzoic acid which was purified by reverse phase HPLC.

Sources & evidence

ORD record: ord-8f30b21be10247199a1cb98efac56dd0
Source dataset: uspto-grants-2016_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09321761B2

Reaction notes

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