HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetonitrile → 3-(4-Bromothiophen-2-yl)-3-hydroxypropanenitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetonitrile | HCID 6342 | — |
| Reactant | 4-Bromothiophene-2-carbaldehyde | HCID 87792 | — |
| Product | 3-(4-Bromothiophen-2-yl)-3-hydroxypropanenitrile | HCID 86694590 | — |
Reaction Steps
Addition of CH3CN to 4-bromothiophene-2-carbaldehyde following the method used in Example 2 gave 3-(4-bromothiophen-2-yl)-3-hydroxypropanenitrile as a light brown oil which was used in the next step without additional purification. Yield (1.95 g, 80%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09447078B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-0b4c34a7edb944d7980955e9f1862dbf |
| Source note | uspto-grants-2016_09 |